Chronic or repeated dehydration is also a risk factor for renal impairment.Chronic exposure to bute is more likely to cause signs attributable to the gastrointestinal tract.” Clinical signs of toxicity include diarrhea, colic, ulceration of the gastrointestinal tract (seen as low protein and/or anemia on blood work or as ulcers on an endoscopic examination), poor hair coat, and weight loss.-agonist oromucosal gel Rx only For Sedation and Restraint in Horses Only NADA #141-306, Approved by FDA Federal law restricts this drug to use by or on the order of a licensed veterinarian.DORMOSEDAN (detomidine hydrochloride) GEL is a synthetic alpha-adrenoreceptor agonist with sedative properties.While the gel sedative has to be prescribed by a vet, a horse owner or trainer can administer it to horses over a year of age.But, as hoof care professionals who have used the product reported in a recent American Farriers Journal email survey maintain, that’s not always easy for owners or trainers to do.
Renal impairment is more prevalent in older horses that have developed issues with their kidney function or with equine athletes that perform strenuous exercise and divert blood flow from their kidneys.
Farriers become concerned about being injured by unruly horses or losing valuable time waiting for the vet to show up to sedate the horse.
Plus, many report dealing with owners who often don’t want to pay to have a vet tranquilize the horse.
DORMOSEDAN GEL produces sedation when administered sublingually at 0.018 mg/lb (0.040 mg/kg).
DORMOSEDAN GEL must be placed beneath the tongue of the horse and is not meant to be swallowed.