Quality of life is greatly affected; patients often find their symptoms to be socially disabling.
Although bowel dysfunction is a common event, to date there have been relatively few studies addressing bowel management.
Above 3.5 kg an inverse association was observed (at 4.5 kg, HR = 0.77 [95% CI, 0.610.96]).
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OUTLINE: This is a randomized, double-blind, placebo-controlled, multicenter study.
Patients are stratified according to disease type (breast vs colorectal female vs colorectal male), age (49 and under vs 50-69 vs 70 and over), ECOG performance status (0-1 vs 2), baseline quality of life (UNISCALE rating less than 50% vs 50-75% vs more than 75%), and concurrent chemotherapy (yes vs no). Choosing to participate in a study is an important personal decision.
Birth weight has inconsistent associations with colorectal cancer, possibly due to different anatomic features of the colon versus the rectum.